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medicube pdrn pink glutathione serum mist 100ml by at M&S Choose Your Bundle:100 Pack
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While drug expulsion from SLNs is caused by a reduction of amorphous regions in the lipid matrix due to a polymorphic transition from the less-ordered α-form to the more-ordered β-form, which reduces the space available for drug molecules, the drug is consequently expelled from the lipid core and may migrate to the particle surface or surrounding medium, leading to a gradual decrease in drug loading efficiency over time (Westesen et al., 1997
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