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The spatially segregated expression of transcription factors, such as HAND1 and NFATC1, further underscores their utility in dissecting the genetic programs governing cardiac morphogenesis
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Within MTR, the Cbl cofactor binds with the DMB group disengaged (‘base-off’), where in some instances a conserved histidine residue can bind as the lower axial ligand (His-off or His-on)
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