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Bladder afferent hyperexcitability in bladder pain syndrome/interstitial cystitis - Yoshimura - 2014 - International Journal of Urology - Wiley Online Library

They concluded “current evidence of the skin-whitening effect of glutathione is still inconclusive… however there is a trend that glutathione might brighten skin colour at sun-exposed area.” A review specifically focusing on topical glutathione (and melanogenesis) found that though topical forms (e.g., GSH 0.5% vs 0.1%) had more effect, the studies were small, short term and lack long‐term data

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one missed cleavage site was allowed, and the carbamidomethylation of cysteine, iTRAQ 4 plex of lysine, and the N-terminus were set as fixed modifications