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Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity - ScienceDirect

54 Acetylation is one of the most frequent and better understood epigenetic changes in histones, neutralizing their charge and generating an open-chromatin configuration which allows the binding of transcription factors and chromatin-remodelling complexes that influence gene transcription

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