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Based on these critical targets, multiple intervention strategies have been developed, including EZH2 inhibitors (tazemetostat and CPI-1205), HDAC inhibitors (vorinostat, entinostat, romidepsin, etc.), BET inhibitors (JQ1/OTX015), DNMT inhibitors (decitabine and azacitidine), as well as approaches targeting specific miRNAs/lncRNAs (miR-21, miR-324-5p, SNHG1, etc.)
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