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The Role of Free Radicals in Pathology and Treatment of Rheumatoid Arthritis | IntechOpen
Diabetic peripheral neuropathy Diabetic neuropathy involves chronic hyperglycemia damaging small blood vessels that feed peripheral nerves (microangiopathy), along with metabolic disruption, oxidative stress, and advanced glycation end-products damaging nerve proteins
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Disruptions in calcium ion metabolism by iron overload in cardiomyocytes are thought to contribute to cardiac dysfunction in such patients (37), while heart fibrosis does not appear to be involved (38)
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