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Ornelas et al., 2020), but again, could be an effect of complex ex vivo systems containing multiple cell types, meaning OPCs/OLs may not be a primary target of rapamycin effects ex vivo (Tang et al., 2002
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These biochemical abnormalities have even been proposed to be diagnostic of ASD as they could predict the presence of ASD with a 98% correct classification rate using Fisher discriminant analysis [18]
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