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Although the drop in hepatic or renal GSH is the most toxicologically relevant interaction (see also below), plasma GSH, free cysteine (Burgunder et al., 1989), and antioxidant capacity (Nuttall et al., 2003) were significantly reduced after a single 2 g PAC administration or 14 days of therapeutic doses of PAC in human volunteers, respectively
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Statistical analyses were performed using SPSS version 21.0 (IBM Corp., USA)
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