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Similarly, the relative intracellular concentrations of aspartate [0.7 mM in liver and 4 mM in brain (293)] versus cysteine [80–100 μM (290)], together with their K M values for cysteine/aspartate aminotransferase [1.6 mM and 22 mM for aspartate and cysteine, respectively (7)], suggest that aspartate would be used preferentially by cysteine/aspartate aminotransferase
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Inflammatory injury parameters, including albumin leakage, proinflammatory cytokines, and neutrophil infiltration, were documented after the admiration of QD-Dox ( 60 of 2.5 μM in erlotinib-resistant A549 cell lines
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