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Who Should Talk to a Doctor First Certain groups should be extra cautious and speak with a clinician before starting glutathione, NAC, or similar antioxidant supplements: Pregnant or breastfeeding individuals People with asthma, since some forms may affect airways Patients with chronic diseases like kidney or liver conditions Anyone undergoing cancer treatment Patients taking multiple prescription medications Supplement quality also matters a great deal

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This provides a clear classification framework and potential directions for subsequent mechanism studies and clinical translation