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, diabetes mellitus) and lactic acidosis Postmenopause Increased uric acid production High cell turnover, e.g.: Enzyme defects, e.g.: [5] Diet rich in protein and especially purine (e.g., red meat, seafood) Obesity Hypercholesterolemia, hypertriglyceridemia Hypertension [7] Sleep apnea [8] [9] Combined decreased excretion and overproduction: high alcohol consumption Organic acids from alcohol metabolism compete with uric acid to be excreted by the kidneys
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