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Figure 3 Collectively, our findings suggest a role for NLRP3-mediated ASC-speck formation and caspase-1 activation in pathologic inflammation associated with moderate and severe forms of COVID-19 supporting potential use of NLRP3 inhibition to mitigate the exacerbated inflammasome-related responses during COVID-19
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It is encoded in gene DLST located on chromosome 14 q24.2-q24.3 with a length of 21815 base pairs [60]
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