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Deep brain stimulation (DBS) for glutaric aciduria type 1. Phenomenology matters when deciding on appropriateness of DBS. Almudena Chacón and colleagues present an interesting case with an excellent outcome in Movement Disorders
The use of valproic acid with or without other anticonvulsants may cause hepatotoxicity and increase plasma ammonia concentrations, leading to encephalopathy
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As illustrated in Table I, most therapeutic strategies remain in the preclinical stage
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