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If any of these signs felt a little too familiar, your body may be trying to tell you something. Glutathione plays a key role in supporting your body's natural detox process, immune

doi: 10.3389/fimmu.2021.689044 Received 31 March 2021 Accepted 10 May 2021 Published 23 June 2021 Volume 12 - 2021 Edited by Narendra Prasad Singh, University of South Carolina, United States Reviewed by José María Pego Reigosa, University Hospital Complex of Vigo, Spain

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Understanding the Innate Repair Receptor (IRR) The innate repair receptor is a heteromeric receptor complex composed of: Erythropoietin receptor (EPOR) β-common receptor (CD131) This receptor is activated in response to: Tissue injury Hypoxia Inflammation Oxidative stress Activation of the IRR triggers a cascade of protective signaling designed to: Limit tissue damage Reduce inflammation Promote cellular survival Support repair rather than scarring ARA-290 was designed specifically to activate this receptor without activating erythropoiesis

helping to protect cells from damage caused by free radicals and reactive oxygen species