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Rather than cataloguing compounds individually, this manuscript synthesizes mechanistic pathways with available human data and evaluates their relevance across breast cancer subtypes, including hormone receptor–positive, HER2-positive, and triple-negative disease
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Classically activated M1 microglia, induced by stimuli such as lipopolysaccharide (LPS) and interferon-gamma (IFN- γ ), release neurotoxic cytokines including IL-1 β and tumor necrosis factor alpha (TNF- α )
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