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For example, a high dose of N-acetylcysteine (1,200 mg/day) paradoxically increased oxidative damage in hypertensive patients, while 600 mg/day reduced MDA by 27% (Szkudlinska et al., 2016)
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CHI usually results from genetic defects that either affect all cells of the pancreatic islets (diffuse CHI) or form a focal lesion (focal CHI)
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