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The studies by Mauro and Chiu exploring vitamin B12 and chronic low back pain showed that daily injections of 1000 pg of cyanocobalamin yielded around 80% reduction in chronic low back pain, whereas injections 3 times per week of 500 pg of methylcobalamin yielded around 30% reduction of pain (10,11)

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Patients frequently experience: Fatigue and generalised weakness that persists despite adequate rest Breathlessness on exertion due to anaemia Palpitations and reduced exercise tolerance Pallor of the skin and mucous membranes These symptoms result from megaloblastic anaemia, where impaired DNA synthesis leads to the production of abnormally large, dysfunctional red blood cells with reduced oxygen-carrying capacity