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This was accompanied by upregulation of inducible nitric oxide synthase (iNOS), IL-1β, and TNF-α, and downregulation of arginase 1 (Arg-1), IL-10, and transforming growth factor-beta (TGF-β)
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It suppresses NF-kB signaling, a master switch for inflammation, and is discussed for systemic inflammatory load (Dalmasso et al., Am J Physiol Gastrointest Liver Physiol, 2008, PMID 18497334)
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