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Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study | Molecular Psychiatry
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Mitophagy is also compromised: whereas wild-type huntingtin participates in autophagic scaffolding, mHTT impairs the recognition and sequestration of damaged mitochondria, allowing dysfunctional organelles to accumulate and promote cellular stress (Rui et al., 2015)
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