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Experiments performed with human PMNs have shown that the binding of IL-8 to its receptor induces the activation of phospholipase A 2 (PLA 2 ), calcium release, and upregulation of the surface expression of N-formyl peptide receptors (Daniels et al., 1992
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Because steatosis is now regarded as a significant risk factor for advanced liver pathology, an understanding of the molecular mechanisms in its etiology provides new therapeutic targets to reverse the alcoholic fatty liver
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