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However, unlike hydroquinone, cysteamine does not have any melanocyte cytotoxic effects.[7] All ten participants in this series experienced substantial improvements in their melasma, in alignment with previous studies where mean reduction in MASI score ranged from 21.3%[5] to 58.8%[4] (at 16 weeks)

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The molecular stability relies heavily on proper handling and storage to minimize degradation by hydrolysis or proteolytic enzymes under laboratory conditions because it is a synthetic peptide analog that does not go through post-translational changes like glycosylation