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Depending on the lineage and tissue specificity, additional functional and phenotypic validation assays for lineage- or tissue-specific iECs can be included: (1) expression of specific venous (NR2F2, EPHB4), arterial (NOTCH1, DLL4, CXCR4, EFNB2, HEY2, ANTXR1) or lymphatic (LYVE-1, PROX1, PDPN) biomarkers (520)
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