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In this regard, the administration of SCREE to NaNO2-treated rats exhibited a significant and dose-dependent ability to elevate the expression of the IL-4 and Bcl2 genes, but also downregulate the expression of TNF-α and tumor suppressor gene P53 in both kidney and liver (Figure 7)
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Oncogene 21 , 3917–3924 (2002)
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