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Mrp2 is probably the most widely studied MRP transporter, primarily because at least two MRP2-deficient rat models (Eisai hyperbilirubinuria rats and TR- rats) are available to study the role of MRP2 in drug disposition (Chen and Tiwari, 2011)
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Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
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