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Additionally, Gal-3 promotes proliferation and metastasis through the Ras-like protein A (RalA)/Ral-binding protein 1 (RalBP1) complex, enhancing cellular MYC (c-MYC) and Yes-associated protein 1 (YAP1) signaling [116]
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HMOX1 expression is upregulated in diabetic myocardial tissues, and knocking down HMOX1 ameliorates ferroptosis, thereby relieving diabetic cardiomyopathy by reducing cardiac fibrosis and improving cardiac function [103]
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