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Neuromuscular blockade is also the primary mechanism of action of several anthelmintic drugs, such as metrifonate, an AChE inhibitor, and levamisole or pyrantel, which act as agonists of nicotinic acetylcholine receptors (nAChRs), the excitatory ligand-gated cation channels that mediate depolarization and contraction of muscle cells [287]
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J Nat Prod (2016) 79:616–28
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