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Examples of hormones that use calcium ions as a second messenger system include angiotensin II, which helps regulate blood pressure through vasoconstriction, and growth hormone-releasing hormone (GHRH), which causes the pituitary gland to release growth hormones
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UACR 100–5,000 mg/g), once-weekly semaglutide (1.0 mg) reduced the risk of the primary composite renal endpoint—defined as kidney failure, sustained ≥50% eGFR decline, or death from renal or cardiovascular causes—by 24% (HR 0.76
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