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Specific research directions include: Pharmacology of lipolysis independent of the growth axis — native fragment 176-191 as a model compound to study how the C-terminal domain of hGH mobilizes fat without stimulating IGF-1 and cell growth Models of obesity — assessment of the impact on adipose tissue metabolism, release and oxidation of free fatty acids and body composition in nutritional and genetic obesity models Separation of growth hormone activity — comparative studies of fragment vs

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